{"id":5965,"date":"2026-04-30T12:29:51","date_gmt":"2026-04-30T12:29:51","guid":{"rendered":"https:\/\/www.ahmetozyigit.com\/?p=5965"},"modified":"2026-04-30T12:44:36","modified_gmt":"2026-04-30T12:44:36","slug":"kendi-biyolojik-yasinizi-kendiniz-belirleyin","status":"publish","type":"post","link":"https:\/\/www.ahmetozyigit.com\/en\/kendi-biyolojik-yasinizi-kendiniz-belirleyin\/","title":{"rendered":"Determine your own biological age!"},"content":{"rendered":"<figure class=\"wp-block-image aligncenter size-full\"><img fetchpriority=\"high\" decoding=\"async\" width=\"890\" height=\"500\" src=\"https:\/\/www.ahmetozyigit.com\/wp-content\/uploads\/2026\/04\/anti-aging-ve-biyolojik-yas.jpg\" alt=\"\" class=\"wp-image-5966\" srcset=\"https:\/\/www.ahmetozyigit.com\/wp-content\/uploads\/2026\/04\/anti-aging-ve-biyolojik-yas.jpg 890w, https:\/\/www.ahmetozyigit.com\/wp-content\/uploads\/2026\/04\/anti-aging-ve-biyolojik-yas-300x169.jpg 300w, https:\/\/www.ahmetozyigit.com\/wp-content\/uploads\/2026\/04\/anti-aging-ve-biyolojik-yas-768x431.jpg 768w, https:\/\/www.ahmetozyigit.com\/wp-content\/uploads\/2026\/04\/anti-aging-ve-biyolojik-yas-18x10.jpg 18w\" sizes=\"(max-width: 890px) 100vw, 890px\" \/><\/figure>\n\n\n\n<p><strong>Age on our identity card<\/strong> with <strong>the true rate of aging of our body<\/strong> It&#039;s not always the same. Calendar age, that is. <strong>chronological age<\/strong>It simply describes the time elapsed since birth. <strong>Biological age<\/strong> Age, on the other hand, is a more functional concept that shows how much our cells, blood vessels, muscles, brain, and metabolism have &quot;worn out.&quot; Biological age measurement methods and &quot;aging clock&quot; studies developed in recent years also reveal significant data supporting this phenomenon, showing us that two people of the same chronological age can be very different in terms of health status, functional capacity, and disease risk.<\/p>\n\n\n\n<p>More importantly, biological age is not a fixed fate or solely a result of genetic inheritance. While genetic factors play a significant role in lifespan, scientific studies show that only a fraction of the differences in lifespan can be explained by genetics, with the remainder related to lifestyle, environmental factors, and metabolic health (Passarino et al., 2016; Shenhar et al., 2026). In other words, genetics gives us a starting point, but how quickly we age is largely determined by how we live.<\/p>\n\n\n\n<p>Many studies show that healthy lifestyle factors (not smoking, healthy weight, regular exercise, good nutrition, good sleep) significantly extend not only lifespan but especially the lifespan free from chronic diseases. Therefore, the goal should not just be to live longer, but to get sick later and to live without prolonged exposure to chronic diseases. Numerous cohort studies have shown that delaying cardiometabolic diseases increases both lifespan and healthy years (Xia et al., 2023; Wang et al., 2024). Therefore, the concept of biological age actually describes exactly this: it&#039;s not how old we are, but how old our body behaves.<\/p>\n\n\n\n<p>The practical significance of this distinction is immense. Because what ages a person is not simply the passage of time, but also the accumulation of metabolic damage, inflammation, atherosclerosis, muscle loss, mitochondrial slowdown, and neurodegenerative processes over the years. Therefore, in modern medicine, aging is no longer defined merely as a process measured by the calendar, but as a process in which biological systems gradually lose function. Chronic cardiometabolic diseases are among the most important factors accelerating this process. Conditions such as insulin resistance, type 2 diabetes, hypertension, visceral obesity, and atherosclerosis are not only diseases affecting specific organs; they are also systemic processes that increase inflammation throughout the body, damage vascular structure, reduce mitochondrial function, and accelerate cellular aging. Therefore, cardiometabolic diseases should be viewed not only as diseases but also as accelerated aging. Similarly, neurodegenerative diseases are not only diseases seen in old age, but are actually manifestations of brain aging resulting from years of inflammation, metabolic disorders, and vascular damage. What these diseases have in common is that most are closely related to lifestyle, which presents us with a very important opportunity: a significant part of our aging process can be modified.<\/p>\n\n\n\n<p>If the goal here is to delay chronic diseases as much as possible and to live a higher quality of life in our 70s and 80s, then there is also an important goal for us in youth and middle age: maintaining the body in optimal physiological balance. That is, not just &quot;avoiding illness&quot;; a well-functioning glucose metabolism, a strong muscular system, well-functioning mitochondria, a balanced immune system, and low inflammation levels are our pre-aging goals. In the field of longevity, the aim is not only to extend life expectancy but also to extend the period of healthy and functional life. In other words, it&#039;s not about being alive at 80, but about being able to exercise at 80, climb stairs without falling, remain mentally productive, and independently manage daily life.<\/p>\n\n\n\n<p>Our bodies need minor stresses to be strong, for our immunity to be at a good level, for cell damage to be repaired, and for our mitochondria to produce energy at healthy levels. This is where a very important concept comes into play: hormesis. Hormesis means that the body becomes stronger when exposed to small and manageable stresses. This is one of the most interesting principles of biology because some things that seem harmful at first glance become beneficial to the body when applied in the right dose. For example, exercise is a stress for muscles, but it strengthens them. Cardio exercise is a stress for mitochondria, but it increases the number of mitochondria. Sauna is a heat stress, but it positively affects vascular function and the cardiovascular system. Cold exposure is a metabolic stress, but it increases metabolic adaptation. Fasting for certain periods is an energy stress, but it activates cellular repair mechanisms. So, controlled stress is a biological signal for &quot;repair and strengthening&quot; (Mattson, 2012; Laukkanen et al., 2018). We can also think of it as, what doesn&#039;t kill you makes you stronger!<\/p>\n\n\n\n<p>Unfortunately, modern life has eliminated much of the physical stress that the human body evolved to be accustomed to. We sit more, walk less, work in sedentary desk jobs that don&#039;t require physical exertion, eat constantly throughout the day, experience almost no real hunger, are exposed to very little temperature change, and spend most of the day in front of screens. We live a comfortable life, but biologically, this comfort comes at a price. Because the human body is a system that evolves under adaptation, not comfort. Muscles atrophy when unused, bones weaken when they don&#039;t bear weight, the heart&#039;s capacity decreases when it&#039;s not strained, the immune system weakens when it&#039;s not stimulated, and mitochondria decrease in number and efficiency when they are not used. There is a very basic rule in biology: Use it or lose it. Because we lose the systems we don&#039;t use, we get sick more often, we get fatter, we get more tired, and we are more susceptible to cardiovascular diseases.<\/p>\n\n\n\n<p>This situation is closely related to the biology of aging. Aging is not simply the passage of time; it is also the slowing of cellular repair mechanisms, decreased mitochondrial function, increased chronic inflammation, and loss of metabolic plasticity. Modern lifestyles create an environment that accelerates precisely these processes: persistently high insulin levels, persistently low exercise, low muscle mass, high inflammation, and low mitochondrial activity. Therefore, we can say that the biggest problem today is not &quot;aging&quot; itself, but &quot;accelerated aging.&quot;<\/p>\n\n\n\n<p><strong>So what can we do about this?<\/strong><\/p>\n\n\n\n<p>Exercise, in particular, is one of the most powerful interventions in this regard. Numerous studies have shown that regular physical activity positively affects not only muscles, but also mitochondria, insulin sensitivity, vascular structure, and even brain health. In fact, some researchers describe exercise as &quot;the most powerful anti-aging drug&quot; because it acts on many aging mechanisms simultaneously (Booth et al., 2012).<\/p>\n\n\n\n<p>Many people cannot find the time for intense and prolonged exercise. However, important studies in recent years have begun to show that the intensity of exercise may be more important than its duration.<\/p>\n\n\n\n<p>New studies, in particular, show that very short but intense bursts of exercise several times a day can be quite effective for cardiovascular health. A study published in Nature in 2025, involving 73,000 people, showed that one minute of high-intensity exercise can provide similar cardiovascular and blood sugar balance benefits to approximately nine minutes of moderate-intensity exercise and about 50\u201360 minutes of walking. Even if you don&#039;t have time to go to the gym, doing four one-minute bursts of intense exercise a day can make a significant difference to your health. These exercises support heart health, help reduce insulin resistance, improve fitness, and boost metabolism.<\/p>\n\n\n\n<p><strong>So what could these 1-minute exercises be?<\/strong><\/p>\n\n\n\n<p>The goal is to push yourself to the point of being breathless and raising your heart rate for that one minute.<\/p>\n\n\n\n<p>Examples:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Climbing stairs very quickly<\/li>\n\n\n\n<li>Running fast in place (high knees)<\/li>\n\n\n\n<li>Doing burpees<\/li>\n\n\n\n<li>Jump rope<\/li>\n\n\n\n<li>Performing squat or lunge movements quickly<\/li>\n\n\n\n<li>Exam<\/li>\n\n\n\n<li>Pedaling very fast on a stationary bike<\/li>\n\n\n\n<li>Walking fast uphill<\/li>\n<\/ul>\n\n\n\n<p>Similarly, periods of fasting, also known as time-restricted eating or intermittent fasting, increase metabolic flexibility. Metabolic flexibility is the body&#039;s capacity to burn glucose when needed and fat when needed. In a constantly eating pattern, the body becomes almost exclusively a glucose-burning system, increasing the risk of insulin resistance and metabolic diseases. Periods of fasting, on the other hand, contribute to lower insulin levels, increased fat burning, and the activation of cellular repair mechanisms (Longo and Panda, 2016).<\/p>\n\n\n\n<p>Previously, dieticians recommended many snacks because it was believed that blood sugar levels should not drop. However, today we know that constantly eating causes insulin to remain high throughout the day. Insulin is not only a hormone that lowers blood sugar; it is also a hormone that increases fat storage and stops fat burning. Therefore, eating frequently throughout the day can make weight loss more difficult, especially for people with insulin resistance.<\/p>\n\n\n\n<p>In time-restricted fasting, the body eats during specific hours of the day, while insulin levels drop during the remaining hours, causing the body to burn fat for energy. This process not only burns fat but also activates the cellular self-cleaning and regeneration mechanisms. This mechanism is called autophagy and is thought to be associated with aging, cancer, Alzheimer&#039;s, and metabolic diseases. Fasting periods put the body under mild stress, activating repair and regeneration mechanisms. In fact, the body becomes stronger when faced with a little challenge.<\/p>\n\n\n\n<p><strong>So how should I eat?<\/strong><\/p>\n\n\n\n<p>Unless you have a serious health problem or a specific condition requiring frequent meals, fasting for certain periods during the day can help you feel more energetic, balance energy levels, and make your metabolism more flexible. Metabolic flexibility is when the body shifts from being a system that constantly burns glucose to one that can burn fat when needed. When this transition occurs, insulin levels become more balanced, fat burning is facilitated, energy fluctuations decrease, and many people describe clearer mental performance and a more stable energy level throughout the day.<\/p>\n\n\n\n<p>It is also important to know that the foods we eat are not solely about calorie intake. Different foods can have different effects on sugar levels in the body. Some foods may increase inflammation levels in the body. Ultra-processed foods, refined carbohydrates, and low-fiber diets can increase the amount of lipopolysaccharide (LPS) that enters the bloodstream by increasing intestinal permeability. This is associated with low-grade chronic inflammation, which is considered one of the fundamental mechanisms of both cardiometabolic and neurodegenerative diseases (Cani et al., 2007).<\/p>\n\n\n\n<p>In contrast, a diet rich in vegetables, fiber, olive oil, polyphenols, and antioxidants creates a biological environment that reduces inflammation and activates cellular defense mechanisms. Specifically, the activation of the cellular defense pathway called NRF2 makes cells more resistant to oxidative stress and inflammation. This pathway can be activated by cruciferous vegetables (broccoli, cauliflower), leafy green vegetables, olive oil, green tea, and many plant-based foods (Hybertson et al., 2011).<\/p>\n\n\n\n<p>In other words, short bursts of intense exercise throughout the day and periods of fasting are two powerful weapons we have to activate our body&#039;s defense mechanisms and make us more resilient.<\/p>\n\n\n\n<p><strong>In short, the human body stays young not under comfort, but through adaptation\u2026<\/strong><\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>Next week: &#039;<strong>Everything is normal\u2026 said the doctor\u2026<\/strong>&#8216;<\/p>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p><strong>Dr. Ahmet \u00d6zyi\u011fit<\/strong> MD, ABAARM<\/p>\n\n\n\n<p>Anti-Aging and Regenerative Medicine Specialist<\/p>\n\n\n\n<p><\/p>","protected":false},"excerpt":{"rendered":"<p>Kimli\u011fimizdeki ya\u015f ile v\u00fccudumuzun ger\u00e7ek ya\u015flanma h\u0131z\u0131 her zaman ayn\u0131 de\u011fildir. Takvim ya\u015f\u0131, yani kronolojik ya\u015f, yaln\u0131zca do\u011fumdan bu yana ge\u00e7en s\u00fcreyi anlat\u0131r. Biyolojik ya\u015f ise h\u00fccrelerimizin, damarlar\u0131m\u0131z\u0131n, kaslar\u0131m\u0131z\u0131n, beynimizin ve metabolizmam\u0131z\u0131n ne kadar \u201cy\u0131prand\u0131\u011f\u0131n\u0131\u201d g\u00f6steren daha i\u015flevsel bir kavramd\u0131r. Son y\u0131llarda geli\u015ftirilen biyolojik ya\u015f \u00f6l\u00e7\u00fcm y\u00f6ntemleri ve \u201caging clock\u201d \u00e7al\u0131\u015fmalar\u0131 da bu olguyu destekleyen [&hellip;]<\/p>","protected":false},"author":2,"featured_media":5966,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-5965","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-genel"],"blocksy_meta":[],"_links":{"self":[{"href":"https:\/\/www.ahmetozyigit.com\/en\/wp-json\/wp\/v2\/posts\/5965","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ahmetozyigit.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.ahmetozyigit.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.ahmetozyigit.com\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ahmetozyigit.com\/en\/wp-json\/wp\/v2\/comments?post=5965"}],"version-history":[{"count":3,"href":"https:\/\/www.ahmetozyigit.com\/en\/wp-json\/wp\/v2\/posts\/5965\/revisions"}],"predecessor-version":[{"id":5970,"href":"https:\/\/www.ahmetozyigit.com\/en\/wp-json\/wp\/v2\/posts\/5965\/revisions\/5970"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.ahmetozyigit.com\/en\/wp-json\/wp\/v2\/media\/5966"}],"wp:attachment":[{"href":"https:\/\/www.ahmetozyigit.com\/en\/wp-json\/wp\/v2\/media?parent=5965"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.ahmetozyigit.com\/en\/wp-json\/wp\/v2\/categories?post=5965"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.ahmetozyigit.com\/en\/wp-json\/wp\/v2\/tags?post=5965"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}